Size does matter: overcoming the adeno-associated virus packaging limit
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چکیده
منابع مشابه
Size does matter: overcoming the adeno-associated virus packaging limit
Recombinant adeno-associated virus (rAAV) vectors mediate long-term gene transfer without any known toxicity. The primary limitation of rAAV has been the small size of the virion (20 nm), which only permits the packaging of 4.7 kilobases (kb) of exogenous DNA, including the promoter, the polyadenylation signal and any other enhancer elements that might be desired. Two recent reports (D Duan et ...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2000
ISSN: 1465-993X
DOI: 10.1186/rr6